Advanced Materials

Fluorinated Graphene for Promoting Neuro-Induction of Stem Cells

Authors

  • Yu Wang,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
    Current affiliation:
    1. These authors contributed equally to this work.
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  • Wong Cheng Lee,

    1. Department of Bioengineering and Department of Mechanical Engineering, Mechanobiology Institute, National University of Singapore, 7 Engineering Drive 1, 117574, Singapore
    Current affiliation:
    1. These authors contributed equally to this work.
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  • Kiran Kumar Manga,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
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  • Priscilla Kailian Ang,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
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  • Jiong Lu,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
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  • Yan Peng Liu,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
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  • Chwee Teck Lim,

    Corresponding author
    1. Department of Bioengineering and Department of Mechanical Engineering, Mechanobiology Institute, National University of Singapore, 7 Engineering Drive 1, 117574, Singapore
    • Department of Bioengineering and Department of Mechanical Engineering, Mechanobiology Institute, National University of Singapore, 7 Engineering Drive 1, 117574, Singapore
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  • Kian Ping Loh

    Corresponding author
    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
    • Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.
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Abstract

Surface engineering of substrates offers the possibility of controlling the physiological functions of cells at the molecular level. Fluorinated graphene promotes the differentiation of MSCs towards neuronal lineages. Cell alignment using printed polydimethylsiloxane channel arrays on fluorinated graphene further enhances the neuro-induction of MSCs even in the absence of chemical inducers.

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