Communication

Liquid Viruses by Nanoscale Engineering of Capsid Surfaces

  1. Avinash J. Patil1,†,
  2. Nina McGrath1,†,
  3. J. Elaine Barclay2,
  4. David J. Evans2,
  5. Helmut Cölfen3,
  6. Ian Manners4,
  7. Adam W. Perriman1,
  8. Stephen Mann1,*

Article first published online: 16 JUL 2012

DOI: 10.1002/adma.201201032

Issue

Advanced Materials

Advanced Materials

Volume 24, Issue 33, pages 4557–4563, August 28, 2012

Additional Information

How to Cite

Patil, A. J., McGrath, N., Barclay, J. E., Evans, D. J., Cölfen, H., Manners, I., Perriman, A. W. and Mann, S. (2012), Liquid Viruses by Nanoscale Engineering of Capsid Surfaces. Adv. Mater., 24: 4557–4563. doi: 10.1002/adma.201201032

Author Information

  1. 1

    Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TS, UK

  2. 2

    Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Colney, Norwich, NR4 7UH UK

  3. 3

    Physikalische Chemie, Universität Konstanz, Universitätsstr. 10, D-78457 Konstanz, Germany

  4. 4

    School of Chemistry, University of Bristol, Bristol BS8 1TS, UK

  1. †

    These authors contributed equally to this work.

*Centre for Organized Matter Chemistry, School of Chemistry, University of Bristol, Bristol BS8 1TS, UK.

Publication History

  1. Issue published online: 20 AUG 2012
  2. Article first published online: 16 JUL 2012
  3. Manuscript Revised: 1 JUN 2012
  4. Manuscript Received: 12 MAR 2012

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Surface engineering of plant virus capsids via cationization (1) and stoichiometric coupling of a polymer surfactant coronal layer (2) produces a highly concentrated, solvent-free liquid virus at 28 °C. These ionic bionanoconstructs are viscoelastic, retain plant infectivity and can be dispersed in a range of organic solvents for aerosol delivery.

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