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Keywords:

  • double emulsions;
  • nanocapsules;
  • iron oxide nanoparticles;
  • hyperthermia;
  • synergic therapy
Thumbnail image of graphical abstract

Iron-oxide-containing double emulsion capsules carrying both hydrophilic and hydrophobic therapeutic molecules can deliver drugs and energy on demand in vivo. Magneto-chemotherapy/hyperthermia involves a burst-like release of hydrophilic doxorubicin and hydrophobic paclitaxel, remotely triggered by a high frequency magnetic field, which also releases energy via internalized iron oxide nanoparticles, all contributing to cell kill.