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Keywords:

  • extracelluar microenviroment;
  • cell culture;
  • soft material;
  • optical projection stereolithography;
  • maskless lithography
Thumbnail image of graphical abstract

The topographic features of the extracelluar matrix (ECM) lay the foundation for cellular behavior. A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated. This robust and versatile platform can generate complex biomimetic scaffolds within seconds. Such 3D scaffolds have promising potentials for studying cell interactions with microenvironments in vitro and in vivo.