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Keywords:

  • Bioelectronics;
  • barrier tissue;
  • PEDOT;
  • toxicology;
  • organic electrochemical transistors
Thumbnail image of graphical abstract

The integration of an organic electrochemical transistor with human barrier tissue cells provides a novel method for assessing toxicology of compounds in vitro. Minute variations in paracellular ionic flux induced by toxic compounds are measured in real time, with unprecedented temporal resolution and extreme sensitivity.