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Keywords:

  • T1T2 dual-modal;
  • synergistic enhancement;
  • molecular imaging;
  • accuracy;
  • liver tumor
Thumbnail image of graphical abstract

Monodisperse Gd2O3-embedded iron oxide (GdIO) nanoparticles can simultaneously enhance the local magnetic field intensities of each other under an external magnetic field and result in synergistic enhancement of T1 and T2 effects. GdIO nanoparticles have the unique property to be both T1 and T2 contrast agents and can potentially lead to higher accuracy in cancer diagnosis, particularly liver tumors.