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Biopsy with Thermally-Responsive Untethered Microtools

Authors

  • Evin Gultepe,

    1. Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA
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  • Jatinder S. Randhawa,

    1. Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA
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  • Sachin Kadam,

    1. Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA
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  • Sumitaka Yamanaka,

    1. Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA
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  • Florin M. Selaru,

    1. Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA
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  • Eun J. Shin,

    1. Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA
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  • Anthony N. Kalloo,

    1. Division of Gastroenterology and Hepatology, Department of Medicine, The Johns Hopkins University, Baltimore, MD 21205, USA
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  • David H. Gracias

    Corresponding author
    1. Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA
    2. Department of Chemistry The Johns Hopkins University, Baltimore, MD 21218, USA
    • Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, MD 21218, USA.
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Abstract

Thermally activated, untethered microgrippers can reach narrow conduits in the body and be used to excise tissue for diagnostic analyses. As depicted in the figure, the feasibility of an in vivo biopsy of the porcine bile duct using untethered microgrippers is demonstrated.

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