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Keywords:

  • hydrophobic interaction;
  • surface chemistry;
  • cell recognition;
  • thermoresponsive materials;
  • nanostructures
Thumbnail image of graphical abstract

Capture and release of cancer cells: a thermoresponsive nanostructured surface is designed to reversibly capture and release cancer cells, wherein hydrophobic interaction helps the realization of target capture/release of cancer cells. The unique nature of the designed platform is based on the synergistic effect of hydrophobic interactions between the smart surface and the hydrophobic anchor (i.e., biotin-BSA), and topographic interactions between the nanostructured substrates and cancer cells.