Frontispiece

Tissue Engineering: Osteophilic Multilayer Coatings for Accelerated Bone Tissue Growth (Adv. Mater. 11/2012)

  1. Nisarg J. Shah,
  2. Jinkee Hong,
  3. Md. Nasim Hyder,
  4. Paula T. Hammond*

Article first published online: 12 MAR 2012

DOI: 10.1002/adma.201290062

Issue

Advanced Materials

Advanced Materials

Volume 24, Issue 11, page 1444, March 15, 2012

Additional Information

How to Cite

Shah, N. J., Hong, J., Hyder, Md. N. and Hammond, P. T. (2012), Tissue Engineering: Osteophilic Multilayer Coatings for Accelerated Bone Tissue Growth (Adv. Mater. 11/2012). Adv. Mater., 24: 1444. doi: 10.1002/adma.201290062

Author Information

  1. Department of Chemical Engineering, The David H. Koch Institute for Integrative Cancer, Research and The Institute for Soldier, Nanotechnologies Massachusetts Institute of Technology 77 Massachusetts Ave, Cambridge, MA 02139 USA

*Department of Chemical Engineering, The David H. Koch Institute for Integrative Cancer, Research and The Institute for Soldier, Nanotechnologies Massachusetts Institute of Technology 77 Massachusetts Ave, Cambridge, MA 02139 USA.

Publication History

  1. Issue published online: 12 MAR 2012
  2. Article first published online: 12 MAR 2012

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Keywords:

  • bone;
  • hydroxyapatite;
  • BMP-2;
  • osteoconductive;
  • layer-by-layer assembly
Thumbnail image of graphical abstract

The development of stable skeletal joint prostheses - con-formal, nanoscale electrostatic coatings capable of de novo bone regeneration - is reported by P. T. Hammond and co-workers on page 1445. These coatings contain a combination of hydroxyapatite and bone growth factor, components which are present in and which regulate the structure of the bone. Osteoblast cells adhere to these coatings and lay down new bone on and around the implant for stable bonding with the surrounding bone tissue.

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