Advanced Materials

Tissue Engineering: Osteophilic Multilayer Coatings for Accelerated Bone Tissue Growth (Adv. Mater. 11/2012)

Authors

  • Nisarg J. Shah,

    1. Department of Chemical Engineering, The David H. Koch Institute for Integrative Cancer, Research and The Institute for Soldier, Nanotechnologies Massachusetts Institute of Technology 77 Massachusetts Ave, Cambridge, MA 02139 USA
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  • Jinkee Hong,

    1. Department of Chemical Engineering, The David H. Koch Institute for Integrative Cancer, Research and The Institute for Soldier, Nanotechnologies Massachusetts Institute of Technology 77 Massachusetts Ave, Cambridge, MA 02139 USA
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  • Md. Nasim Hyder,

    1. Department of Chemical Engineering, The David H. Koch Institute for Integrative Cancer, Research and The Institute for Soldier, Nanotechnologies Massachusetts Institute of Technology 77 Massachusetts Ave, Cambridge, MA 02139 USA
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  • Paula T. Hammond

    Corresponding author
    1. Department of Chemical Engineering, The David H. Koch Institute for Integrative Cancer, Research and The Institute for Soldier, Nanotechnologies Massachusetts Institute of Technology 77 Massachusetts Ave, Cambridge, MA 02139 USA
    • Department of Chemical Engineering, The David H. Koch Institute for Integrative Cancer, Research and The Institute for Soldier, Nanotechnologies Massachusetts Institute of Technology 77 Massachusetts Ave, Cambridge, MA 02139 USA.
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Abstract

The development of stable skeletal joint prostheses - con-formal, nanoscale electrostatic coatings capable of de novo bone regeneration - is reported by P. T. Hammond and co-workers on page 1445. These coatings contain a combination of hydroxyapatite and bone growth factor, components which are present in and which regulate the structure of the bone. Osteoblast cells adhere to these coatings and lay down new bone on and around the implant for stable bonding with the surrounding bone tissue.

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