Theranostics: Mesoporous Silica-Coated Gold Nanorods as a Light-Mediated Multifunctional Theranostic Platform for Cancer Treatment (Adv. Mater. 11/2012)

Authors

  • Zhenjiang Zhang,

    1. CAS Key Laboratory for Biomedical, Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    Search for more papers by this author
  • Liming Wang,

    1. CAS Key Laboratory for Biomedical, Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    2. Institute of High Energy Physics, Chinese Academy of Sciences, No.19B Yuquanlu, Beijing 100049, China
    Search for more papers by this author
  • Jing Wang,

    1. CAS Key Laboratory for Biomedical, Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    Search for more papers by this author
  • Xiumei Jiang,

    1. CAS Key Laboratory for Biomedical, Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    Search for more papers by this author
  • Xiaohui Li,

    1. CAS Key Laboratory for Biomedical, Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    Search for more papers by this author
  • Zhijian Hu,

    1. CAS Key Laboratory of Standardization and Measurement for Nanotechnology, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    Search for more papers by this author
  • Yinglu Ji,

    1. CAS Key Laboratory of Standardization and Measurement for Nanotechnology, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    Search for more papers by this author
  • Xiaochun Wu,

    Corresponding author
    1. CAS Key Laboratory of Standardization and Measurement for Nanotechnology, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    • CAS Key Laboratory of Standardization and Measurement for Nanotechnology, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    Search for more papers by this author
  • Chunying Chen

    Corresponding author
    1. CAS Key Laboratory for Biomedical, Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China
    • CAS Key Laboratory for Biomedical, Effects of Nanomaterials and Nanosafety, National Center for Nanoscience and Technology, No.11 Zhongguancun Beiyitiao, Beijing 100190, China.
    Search for more papers by this author

Abstract

original image

On page 1418 X. Wu, C. Chen, and co-workers develop mesoporous silica-coated gold nanorods (Au@SiO2) as a versatile platform for imaging, chemotherapeutics, and hyperthermia. The Au@SiO2 thus keeps both the unique functions of mesoporous silica nanoparticles and gold nanorods, and also provides a new functionality: lightcontrolled drug release. With integrated functions, such multifunctional theranostic systems are critical to optimize therapeutic efficacy and to improve safety of therapeutic regimes. They will provide more opportunities for on-demand therapy, paving the way to personalized medicine.

Ancillary