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Keywords:

  • graphene oxide nanocomposites;
  • magnetic resonance imaging;
  • photoacoustic imaging;
  • photothermal therapy;
  • multimodal imaging
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A nanoscale reduced graphene oxide–iron oxide nanoparticle (RGO–IONP) complex is nonco-valently functionalized with polyethylene glycol (PEG) by Z. Liu and co-workers on page 1868, obtaining a RGO–IONP–PEG nanocomposite which displays excellent physiological stability, strong NIR optical absorbance, and superpara-magnetic properties. This theranostic nanoprobe allows multimodal tumor imaging - in vivo triple modal fluorescence, photoacoustic, and magnetic resonance imaging are carried out, uncovering high passive tumor targeting, which is further used for the effective photothermal ablation of tumors in mice.