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DNA Hybridization: Direct Attachment of Microbial Organisms to Material Surfaces Through Sequence-Specific DNA Hybridization (Adv. Mater. 18/2012)

  1. Amy A. Twite,
  2. Sonny C. Hsiao,
  3. Hiroaki Onoe,
  4. Richard A. Mathies,
  5. Matthew B. Francis*

Article first published online: 2 MAY 2012

DOI: 10.1002/adma.201290104

Issue

Advanced Materials

Advanced Materials

Volume 24, Issue 18, page 2365, May 8, 2012

Additional Information

How to Cite

Twite, A. A., Hsiao, S. C., Onoe, H., Mathies, R. A. and Francis, M. B. (2012), DNA Hybridization: Direct Attachment of Microbial Organisms to Material Surfaces Through Sequence-Specific DNA Hybridization (Adv. Mater. 18/2012). Adv. Mater., 24: 2365. doi: 10.1002/adma.201290104

Author Information

  1. Department of Chemistry, University of California, Berkeley, and Lawrence Berkeley National Laboratory, Materials Sciences Division, Berkeley, CA 94720-1460, USA

*Department of Chemistry, University of California, Berkeley, and Lawrence Berkeley National Laboratory, Materials Sciences Division, Berkeley, CA 94720-1460, USA.

Publication History

  1. Issue published online: 2 MAY 2012
  2. Article first published online: 2 MAY 2012

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Keywords:

  • DNA;
  • microbial cells;
  • photosynthetic organisms;
  • nitrogen fixation;
  • surface patterning
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M. B. Francis and co-workers develop a new chemical method for the attachment of single-stranded DNA molecules to the surfaces of these organisms. On page 2380, they describe how, when exposed to substrates bearing the sequence complements, the microbes can be attached to specified locations with very high efficiency. The use of multiple DNA sequences allows complex microbial ‘communities’ to be generated, potentially allowing the study of symbiotic relationships. Shown are Synechocystis (red), Saccharomyces cerevisiae (green), and Azotobacter vinelandii (blue).

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