• graphene oxide;
  • nanotechnology;
  • optical biosensors;
  • photoluminescence;
  • fluorescence resonance energy transfer
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As an oxygenated lattice of donor/acceptor molecules exposed in a planar surface, graphene oxide enables unprecedented optical biosensing strategies to detect DNA, cancer biomarkers, viruses, and more. It has excellent capabilities for direct wiring with biomolecules, heterogeneous chemical and electronic structures, the ability to be solution-processed, and the ability to be tuned as either an insulator, semiconductor or semi-metal. On page 3298, E. Morales-Narváez and A. Merkoçi discuss the rationale behind the use of graphene oxide in biosensing applications and review current approaches.