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Hydrogels: Mosaic Hydrogels: One-Step Formation of Multiscale Soft Materials (Adv. Mater. 27/2012)

  1. Lian Leng1,
  2. Arianna McAllister2,
  3. Boyang Zhang2,3,
  4. Milica Radisic2,3,
  5. Axel Günther1,2,*

Article first published online: 10 JUL 2012

DOI: 10.1002/adma.201290166

Issue

Advanced Materials

Advanced Materials

Volume 24, Issue 27, page 3582, July 17, 2012

Additional Information

How to Cite

Leng, L., McAllister, A., Zhang, B., Radisic, M. and Günther, A. (2012), Hydrogels: Mosaic Hydrogels: One-Step Formation of Multiscale Soft Materials (Adv. Mater. 27/2012). Adv. Mater., 24: 3582. doi: 10.1002/adma.201290166

Author Information

  1. 1

    Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario, M5S3G8, Canada

  2. 2

    Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario, M5S 3G9, Canada

  3. 3

    Department of Chemical Engineering and Applied Chemistry, University of Toronto, 200 College Street, Toronto, Ontario, M5S 3E5, Canada

*Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario, M5S3G8, Canada.

Publication History

  1. Issue published online: 10 JUL 2012
  2. Article first published online: 10 JUL 2012

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Keywords:

  • hydrogels;
  • hierarchical materials;
  • biomaterials;
  • encoding;
  • 3D cell culture;
  • 3D tissues
Thumbnail image of graphical abstract

A one-step, continuous formation of mosaic hydrogels is described by A. Günther and coworkers on page 3650. A multilayer microfluidic platform enables a secondary biopolymer to be dynamically incorporated within a flowing biopolymer sheet prior to cross-linking. Stacked or tubular mosaic hydrogel assemblies with millimeter to centimeter length scales are created, as well as tesselations with locally varying composition, and primary cells could be incorporated. In addition, information may be stored and recorded.

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