Advanced Materials

Hydrogels: Mosaic Hydrogels: One-Step Formation of Multiscale Soft Materials (Adv. Mater. 27/2012)

Authors

  • Lian Leng,

    1. Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario, M5S3G8, Canada
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  • Arianna McAllister,

    1. Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario, M5S 3G9, Canada
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  • Boyang Zhang,

    1. Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario, M5S 3G9, Canada
    2. Department of Chemical Engineering and Applied Chemistry, University of Toronto, 200 College Street, Toronto, Ontario, M5S 3E5, Canada
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  • Milica Radisic,

    1. Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario, M5S 3G9, Canada
    2. Department of Chemical Engineering and Applied Chemistry, University of Toronto, 200 College Street, Toronto, Ontario, M5S 3E5, Canada
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  • Axel Günther

    Corresponding author
    1. Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario, M5S3G8, Canada
    2. Institute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, Ontario, M5S 3G9, Canada
    • Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario, M5S3G8, Canada.
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Abstract

A one-step, continuous formation of mosaic hydrogels is described by A. Günther and coworkers on page 3650. A multilayer microfluidic platform enables a secondary biopolymer to be dynamically incorporated within a flowing biopolymer sheet prior to cross-linking. Stacked or tubular mosaic hydrogel assemblies with millimeter to centimeter length scales are created, as well as tesselations with locally varying composition, and primary cells could be incorporated. In addition, information may be stored and recorded.

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