Tissue Engineering: Fluorinated Graphene for Promoting Neuro-Induction of Stem Cells (Adv. Mater. 31/2012)

Authors

  • Yu Wang,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
    Current affiliation:
    1. These authors contributed equally to this work.
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  • Wong Cheng Lee,

    1. Department of Bioengineering and Department of Mechanical Engineering, Mechanobiology Institute, National University of Singapore, 7 Engineering Drive 1, 117574, Singapore
    Current affiliation:
    1. These authors contributed equally to this work.
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  • Kiran Kumar Manga,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
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  • Priscilla Kailian Ang,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
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  • Jiong Lu,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
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  • Yan Peng Liu,

    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
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  • Chwee Teck Lim,

    Corresponding author
    1. Department of Bioengineering and Department of Mechanical Engineering, Mechanobiology Institute, National University of Singapore, 7 Engineering Drive 1, 117574, Singapore
    • Department of Bioengineering and Department of Mechanical Engineering, Mechanobiology Institute, National University of Singapore, 7 Engineering Drive 1, 117574, Singapore
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  • Kian Ping Loh

    Corresponding author
    1. Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore
    • Graphene Research Centre and Department of Chemistry, National University of Singapore, 3 Science Drive 3, 117543, Singapore.
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Abstract

original image

Surfaces with good biocompatibility and tissue-specific inductive capabilities are highly desirable in various tissue engineering and cell therapeutic applications. On page 4285, K. P. Loh, C. T. Lim, and co-workers show that mesenchymal stem cells (MSCs) can be controllably patterned on fluorinated graphene, triggering alignment-induced neuronal differentiation. Their results point to a large-scale and rapid strategy to align MSCs and the ability to induce neuronal lineage in the absence of chemical inducer.

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