Low Power Upconverted Near-IR Light for Efficient Polymeric Nanoparticle Degradation and Cargo Release

Authors

  • Mathieu L. Viger,

    1. Skaggs School of Pharmacy and Pharmaceutical Sciences, Departments of NanoEngineering and of Materials Science and Engineering, University of California at San Diego, La Jolla, CA, 92093, USA
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  • Madeleine Grossman,

    1. Department of Chemistry and Biochemistry, University of California at San Diego, La Jolla, CA, 92093, USA
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  • Nadezda Fomina,

    1. Skaggs School of Pharmacy and Pharmaceutical Sciences, Departments of NanoEngineering and of Materials Science and Engineering, University of California at San Diego, La Jolla, CA, 92093, USA
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  • Adah Almutairi

    Corresponding author
    1. Skaggs School of Pharmacy and Pharmaceutical Sciences, Departments of NanoEngineering and of Materials Science and Engineering, University of California at San Diego, La Jolla, CA, 92093, USA
    • Skaggs School of Pharmacy and Pharmaceutical Sciences, Departments of NanoEngineering and of Materials Science and Engineering, University of California at San Diego, La Jolla, CA, 92093, USA.
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Abstract

original image

By encapsulating NaYF4:Tm.Yb upconverting nanocrystals in UV-degradable polymer capsules, it is possible to access efficient polymer photodegradation and remotely controlled release using near-IR laser light at an unprecedentedly low power.

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