Advanced Materials

Clay: New Opportunities for Tissue Regeneration and Biomaterial Design

Authors

  • Jonathan I. Dawson,

    Corresponding author
    1. Institute of Developmental Sciences University of Southampton Southampton, SO16 6YD, UK
    • Institute of Developmental Sciences University of Southampton Southampton, SO16 6YD, UK.
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  • Richard O. C. Oreffo

    Corresponding author
    1. Institute of Developmental Sciences University of Southampton Southampton, SO16 6YD, UK
    • Institute of Developmental Sciences University of Southampton Southampton, SO16 6YD, UK.
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Abstract

Seminal recent studies that have shed new light on the remarkable properties of clay interactions suggest unexplored opportunities for biomaterial design and regenerative medicine. Here, recent conceptual and technological developments in the science of clay interactions with biomolecules, polymers, and cells are examined, focusing on the implications for tissue engineering and regenerative strategies. Pioneering studies demonstrating the utility of clay for drug-delivery and scaffold design are reviewed and areas for future research and development highlighted.

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