The authors wish to dedicate this paper to the memory of Officer Sean Collier, for his caring service to the MIT community and for his sacrifice.
Fluorescent Multiblock π-Conjugated Polymer Nanoparticles for In Vivo Tumor Targeting†
Article first published online: 24 JUN 2013
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Volume 25, Issue 32, pages 4504–4510, August 27, 2013
How to Cite
Ahmed, E., Morton, S. W., Hammond, P. T. and Swager, T. M. (2013), Fluorescent Multiblock π-Conjugated Polymer Nanoparticles for In Vivo Tumor Targeting. Adv. Mater., 25: 4504–4510. doi: 10.1002/adma.201301656
- Issue published online: 19 AUG 2013
- Article first published online: 24 JUN 2013
- Manuscript Revised: 16 MAY 2013
- Manuscript Received: 13 APR 2013
- block copolymers;
- conjugated polymers;
- fluorescent bioimaging;
- tumor targeting
Highly fluorescent multiblock conjugated polymer nanoparticles with folic acid surface ligands are highly effective for bioimaging and in vivo tumor targeting. The targeted nanoparticles were preferentially localized in tumor cells in vivo, thereby illustrating their potential for diagnostic and therapeutic applications.