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3D Graphene Oxide–Polymer Hydrogel: Near-Infrared Light-Triggered Active Scaffold for Reversible Cell Capture and On-Demand Release

Authors

  • Wen Li,

    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences, Changchun Institute of Applied Chemistry Chinese Academy of Sciences, Changchun, Jilin, China
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  • Jiasi Wang,

    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences, Changchun Institute of Applied Chemistry Chinese Academy of Sciences, Changchun, Jilin, China
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  • Jinsong Ren,

    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences, Changchun Institute of Applied Chemistry Chinese Academy of Sciences, Changchun, Jilin, China
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  • Xiaogang Qu

    Corresponding author
    1. Laboratory of Chemical Biology, Division of Biological Inorganic Chemistry State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry Graduate School of the Chinese Academy of Sciences, Changchun Institute of Applied Chemistry Chinese Academy of Sciences, Changchun, Jilin, China
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Abstract

An active cell scaffold based on a graphene–polymer hydrogel has been successfully fabricated. The macroporous hydrogel can efficiently capture cells not only through the bioadhesive ligand RGD but also through on-demand release of cells with an NIR light stimulus. The latter process shows better dynamic control over cells than traditional passive-hydrogel-based cell depots.

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