Advanced Materials

Cancer Treatment: Incorporating Graphene Oxide and Gold Nanoclusters: A Synergistic Catalyst with Surprisingly High Peroxidase-Like Activity Over a Broad pH Range and its Application for Cancer Cell Detection (Adv. Mater. 18/2013)

Authors

  • Yu Tao,

    1. State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun, Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences, Changchun, Jilin 130022, China, Fax: 86-431-85262625
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  • Youhui Lin,

    1. State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun, Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences, Changchun, Jilin 130022, China, Fax: 86-431-85262625
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  • Zhenzhen Huang,

    1. State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun, Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences, Changchun, Jilin 130022, China, Fax: 86-431-85262625
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  • Jinsong Ren,

    Corresponding author
    1. State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun, Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences, Changchun, Jilin 130022, China, Fax: 86-431-85262625
    • State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun, Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences, Changchun, Jilin 130022, China, Fax: 86-431-85262625.===

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  • Xiaogang Qu

    Corresponding author
    1. State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun, Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences, Changchun, Jilin 130022, China, Fax: 86-431-85262625
    • State Key Laboratory of Rare Earth Resource Utilization and Laboratory of Chemical Biology, Changchun, Institute of Applied Chemistry, Graduate School of the Chinese Academy of Sciences Chinese Academy of Sciences, Changchun, Jilin 130022, China, Fax: 86-431-85262625.===

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Abstract

Graphene oxide (GO) can serve as the enzyme modulator to regulate the peroxidase-like activity of the Au nanoclusters (AuNCs), as reported by Xiaogang Qu, Jinsong Ren, and co-workers on page 2594. The most exciting feature of the GO-AuNCs hybrid is that it exhibits high catalytic activity over a broad pH range, and even at neutral pH. Inspired by this, the hybrid can also be applied as a robust nanoprobe for selective, quantitative, and fast colorimetric detection of cancer cells.

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