Self-Assembly: A Robust Route to Enzymatically Functional, Hierarchically Self-Assembled Peptide Frameworks (Adv. Mater. 19/2013)



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Adding enzyme biofunctionality to peptide nanofibers is challenging since this can inhibit enzyme activity and peptide self-assembly. Easan Sivaniah and co-workers demonstrate on page 2661 the attachment of a polymerization synthase to peptide nanofibers via a selective non-covalent peptide tag. The biofunctionalization, rapidly achieved, generates a biocompatible biopolyester coat on the fibers, with applicability in biomedical engineering. Cover image by Effigos AG.