Advanced Materials

Hydrogels: In Situ Self-Folding Assembly of a Multi-Walled Hydrogel Tube for Uniaxial Sustained Molecular Release (Adv. Mater. 39/2013)

Authors

  • Kwanghyun Baek,

    1. Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
    Search for more papers by this author
  • Jae Hyun Jeong,

    1. Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
    Search for more papers by this author
  • Artem Shkumatov,

    1. Department of Pathobiology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
    Search for more papers by this author
  • Rashid Bashir,

    1. Department of Electrical and Computer Engineering, Department of Bioengineering, Micro and Nano Technology Lab, Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
    Search for more papers by this author
  • Hyunjoon Kong

    Corresponding author
    1. Department of Chemical and Biomolecular Engineering, Micro and Nanotechnology Laboratory, Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA
    • Department of Chemical and Biomolecular Engineering, Micro and Nanotechnology Laboratory, Institute of Genomic Biology, University of Illinois at Urbana-Champaign, Urbana Illinois 61801 USA

    Search for more papers by this author

Abstract

Multiwalled poly(ethylene glycol) diacrylate (PEGDA) hydrogel tubes are assembled via in situ self-folding of a bilayered hydrogel patch with different expansion ratios and rigidity between the two layers, as described by Hyunjoon Kong and co-workers on page 5568. The resulting gel tubes exhibit unidirectional, sustained release of proangiogenic growth factors and significantly stimulated vascularization around the gel implant.

image

Ancillary