Towards Protein Field-Effect Transistors: Report and Model of a Prototype (pages 816–822)
G. Maruccio, A. Biasco, P. Visconti, A. Bramanti, P. P. Pompa, F. Calabi, R. Cingolani, R. Rinaldi, S. Corni, R. Di Felice, E. Molinari, M. P. Verbeet and G. W. Canters
Article first published online: 30 MAR 2005 | DOI: 10.1002/adma.200400628
A protein field-effect transistor (Pro-FET) based on the blue-copper protein azurins (see Figure) and operating at room temperature and ambient pressure is demonstrated. The transfer characteristics of the Pro-FET exhibit a pronounced resonance due to the switch from behaving as a n-metal oxide semiconductor FET (n-MOSFET) to a p-MOSFET. Carrier transport through the device is explained in terms of an equilibrium between the two possible oxidation states of the redox site (Cu1+ and Cu2+).