Biological Containers: Protein Cages as Multifunctional Nanoplatforms (pages 1025–1042)
M. Uchida, M. T. Klem, M. Allen, P. Suci, M. Flenniken, E. Gillitzer, Z. Varpness, L. O. Liepold, M. Young and T. Douglas
Article first published online: 16 APR 2007 | DOI: 10.1002/adma.200601168
Biological systems fabricate materials under mild synthetic conditions using self-assembled macromolecular templates. Containerlike protein architectures such as viral capsids and ferritin are examples of such biological templates. Three distinct interfaces can be synthetically exploited: the interior, the exterior, and the interface between subunits (see figure). Recent studies investigating the development of some containerlike protein-cage architectures for material synthesis are presented in this article.