Bone-like Resorbable Silk-based Scaffolds for Load-bearing Osteoregenerative Applications (pages 75–78)
Andrew M. Collins, Nick J. V. Skaer, Tom Gheysens, David Knight, Caroline Bertram, Helmtrud I. Roach, Richard O. C. Oreffo, Sonja Von-Aulock, Teodora Baris, John Skinner and Stephen Mann
Version of Record online: 10 NOV 2008 | DOI: 10.1002/adma.200802239
Hydroxyapatite/silk biocompatible composites with unprecedented mechanical strength and toughness areproduced in a new process with theintegrated mineralization of macroporous silk fibroin scaffolds. Thebiomimetic bone-like composites areabsorbable and load-bearing with compressive strength, modulus, andtoughness comparable to the mechanical tolerances of cancellous bone.