The Effect of NaF In Vitro on the Mechanical and Material Properties of Trabecular and Cortical Bone (pages 451–457)
Philipp J. Thurner, Blake Erickson, Patricia Turner, Ralf Jungmann, Jason Lelujian, Alexander Proctor, James C. Weaver, Georg Schitter, Daniel E. Morse and Paul K. Hansma
Article first published online: 25 NOV 2008 | DOI: 10.1002/adma.200801204
High doses of sodium fluoride in bones lead to severe softening, by weakening interfacial properties between the inorganic minerals and the organic components, while leaving mineralization unchanged. This leads to reduction of microdamage and associated stress-whitening pointing to a change in failure mode. Accordingly, elastic modulus, failure stress, and indentation-distance increase are decreased, whereas failure strain is increased.