A Novel Family of Biodegradable Poly(ester amide) Elastomers (pages H95–H100)
Hao Cheng, Paulina S. Hill, Daniel J. Siegwart, Nathaniel Vacanti, Abigail K. R. Lytton-Jean, Seung-Woo Cho, Anne Ye, Robert Langer and Daniel G. Anderson
Article first published online: 10 MAR 2011 | DOI: 10.1002/adma.201003482
Biodegradable elastomeric materials have particular utility in tissue engineering applications because their compliance under force closely resembles the elastic nature of many human tissues. A family of biodegradable poly(ester amide) elastomers were developed, with excellent elasticity under hydrated conditions, good in vivo biocompatibility and a slow degradation rate. This study sheds light on the structure-property relationship behind designing biodegradable elastomeric materials.