Microfabricated Biomaterials for Engineering 3D Tissues (pages 1782–1804)
Pinar Zorlutuna, Nasim Annabi, Gulden Camci-Unal, Mehdi Nikkhah, Jae Min Cha, Jason W. Nichol, Amir Manbachi, Hojae Bae, Shaochen Chen and Ali Khademhosseini
Article first published online: 13 MAR 2012 | DOI: 10.1002/adma.201104631
Microfabrication approaches for engineering three-dimensional biomimetic tissues are reviewed. Initially fabrication methods for generating structures that are capable of directing cell function are discussed. Subsequently, the applications of these methods in tissue engineering and regenerative medicine towards creating vasculature, directing stem cell differentiation and regulating cellular interactions are highlighted.