Lasers based on biomaterials known as Generally-Recognized-As-Safe (GRAS) substances approved by the U.S. Food and Drug Administration (FDA) are demonstrated. Vitamin B2-doped microdroplet lasers are generated and trapped on a super-hydrophobic poly-L-lactic acid substrate. The spheres support whispering gallery mode lasing at optical pump energies as low as 15 nJ per pulse (≈1 kW/mm2).
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