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Keywords:

  • label-free biosensing;
  • microcavity mode broadening;
  • whispering gallery mode;
  • rayleigh scattering;
  • nanoparticle detection
Thumbnail image of graphical abstract

A new label-free sensing mechanism is demonstrated experimentally by monitoring the whispering-gallery mode broadening in microcavities. It is immune to both noise from the probe laser and environmental disturbances, and is able to remove the strict requirement for ultra-high-Q mode cavities for sensitive nanoparticle detection. This ability to sense nanoscale objects and biological analytes is particularly crucial for wide applications.