High Ionic Strength Formation of DOPA-Melanin Coating for Loading and Release of Cationic Antimicrobial Compounds

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Abstract

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Conformal DOPA-melanin films are formed on a variety of substrates by simple dip-coating in an alkaline DOPA solution at high ionic strength. Compared to polydopamine, DOPA-melanin coatings have the advantage of high hydrophilicity and also the ability to bind and release cations. The latter is demonstrated by using DOPA-melanin coated polycarbonate to form an antibacterial surface that inhibits and kills S. aureus.

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