Communication

Organocatalytic and Enantioselective Direct Vinylogous Michael Addition to Maleimides

  1. Jun Lu,
  2. Wei-Juan Zhou,
  3. Feng Liu,
  4. Teck-Peng Loh

Article first published online: 24 JUL 2008

DOI: 10.1002/adsc.200800259

Issue

Advanced Synthesis & Catalysis

Advanced Synthesis & Catalysis

Volume 350, Issue 11-12, pages 1796–1800, August 4, 2008

Additional Information

How to Cite

Lu, J., Zhou, W.-J., Liu, F. and Loh, T.-P. (2008), Organocatalytic and Enantioselective Direct Vinylogous Michael Addition to Maleimides. Adv. Synth. Catal., 350: 1796–1800. doi: 10.1002/adsc.200800259

Author Information

  1. Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 1 Nanyang Link, Singapore 637371, Fax: (+65)-6791-1961; phone: (+65)-6316-8899

Publication History

  1. Issue published online: 31 JUL 2008
  2. Article first published online: 24 JUL 2008
  3. Manuscript Received: 30 APR 2008

Funded by

  • A*STAR. Grant Number: 072101 0024

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Keywords:

  • Cinchona alkaloids;
  • dicyanoolefins;
  • enantioselective Michael addition;
  • maleimides;
  • organocatalysis

Abstract

An organocatalytic enantioselective direct vinylogous Michael addition of α,α-dicyanoolefins to maleimide has been developed; the products could be obtained in good yields and high enantioselectivities.

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