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Palladium on Charcoal as a Recyclable Catalyst for C![[BOND]](http://onlinelibrarystatic.wiley.com/undisplayable_characters/00f8ff.gif)
S Cross-Coupling of Thiols with Aryl Halides under Ligand-Free Conditions
Article first published online: 21 OCT 2009
DOI: 10.1002/adsc.200900501
Copyright © 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Jiang, Z., She, J. and Lin, X. (2009), Palladium on Charcoal as a Recyclable Catalyst for CS Cross-Coupling of Thiols with Aryl Halides under Ligand-Free Conditions. Advanced Synthesis & Catalysis, 351: 2558–2562. doi: 10.1002/adsc.200900501
Publication History
- Issue published online: 5 NOV 2009
- Article first published online: 21 OCT 2009
- Manuscript Received: 17 JUL 2009
Funded by
- National Natural Science Foundation of China. Grant Numbers: 20702047, J0830413
- Natural Science Foundation of Zhejiang Province. Grant Numbers: R407106, Y4090028
Keywords:
- aryl sulfides;
- cross-coupling;
- heterogeneous catalysis;
- palladium on charcoal
Graphical Abstract
Abstract
S-Arylation of a wide variety of substituted aryl and aliphatic thiols with aryl halides using a catalytic amount of palladium on charcoal as a heterogeneous catalysis with potassium hydroxide as the base in dimethyl sulfoxide (DMSO) at 110 °C is accomplished in good yields. The CS bond formation reaction functions under ligand-free conditions, and the palladium on charcoal catalyst can be is reused for five runs without any loss of activity.