1615-4169/asset/2258_left.gif?v=1&s=480b85eb3acd0e8f47639c75e9ec7a59d53cd074)
Communication
Facile and Efficient Synthesis of Hydrophenanthren-1(2H)-ones and Naphtho[2,1-c]furan-3(1H)-ones by a Palladium-Catalyzed Aryne Annulation Strategy
Article first published online: 9 FEB 2010
DOI: 10.1002/adsc.200900703
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Huang, X., Sha, F. and Tong, J. (2010), Facile and Efficient Synthesis of Hydrophenanthren-1(2H)-ones and Naphtho[2,1-c]furan-3(1H)-ones by a Palladium-Catalyzed Aryne Annulation Strategy. Adv. Synth. Catal., 352: 379–385. doi: 10.1002/adsc.200900703
Publication History
- Issue published online: 17 FEB 2010
- Article first published online: 9 FEB 2010
- Manuscript Received: 10 OCT 2009
Funded by
- National Natural Science Foundation of China. Grant Numbers: 20872127, 20732005, J0830431
- National Basic Research Program of China. Grant Number: 973 Program, 2009CB825300
- CAS Academician Foundation of Zhejiang Province
Keywords:
- allylvinyl iodides;
- annulation;
- arynes;
- hydrophenanthren-1(2H)-ones;
- naphtho[2,1-c]furan-3(1H)-ones;
- palladium
Abstract
Novel palladium-catalyzed carboannulation reactions of arynes with functionalized vinyl iodides are reported. By applying allyl-substituted iodocycloenones and iodofuranones, a series of hydrophenanthren-1(2H)-ones and naphtho[2,1-c]furan-3(1H)-ones were efficiently constructed in one pot under mild conditions.