Communication

Highly Linear-Selective Hydroformylation of 1-Alkenes using Formaldehyde as a Syngas Substitute

  1. Gouki Makado1,
  2. Tsumoru Morimoto1,
  3. Yasuko Sugimoto1,
  4. Ken Tsutsumi1,
  5. Natsuko Kagawa2,
  6. Kiyomi Kakiuchi1

Article first published online: 9 FEB 2010

DOI: 10.1002/adsc.200900713

Issue

Advanced Synthesis & Catalysis

Advanced Synthesis & Catalysis

Volume 352, Issue 2-3, pages 299–304, February 15, 2010

Additional Information

How to Cite

Makado, G., Morimoto, T., Sugimoto, Y., Tsutsumi, K., Kagawa, N. and Kakiuchi, K. (2010), Highly Linear-Selective Hydroformylation of 1-Alkenes using Formaldehyde as a Syngas Substitute. Adv. Synth. Catal., 352: 299–304. doi: 10.1002/adsc.200900713

Author Information

  1. 1

    Graduate School of Materials Science, Nara Institute of Science and Technology (NAIST), Takayama, Ikoma, Nara 630-0192, Japan, Fax: (+81)-743-72-6081

  2. 2

    Department of Medicinal Organic Chemistry, Chiba University Yayoi, Inage, Chiba 263-8522, Japan

Publication History

  1. Issue published online: 17 FEB 2010
  2. Article first published online: 9 FEB 2010
  3. Manuscript Revised: 30 NOV 2009
  4. Manuscript Received: 14 OCT 2009

Funded by

  • Grant-in-Aid for Scientific Research
  • Priority Areas “Advanced Molecular Transformations of Carbon Resouces”
  • MEXT

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Keywords:

  • alkenes;
  • formaldehyde;
  • homogeneous catalysis;
  • hydroformylation;
  • rhodium

Abstract

A highly linear-selective hydroformylation of 1-alkenes using formaldehyde without the direct use of syngas is described. One rhodium(I) complex catalyzes two processes in the overall hydroformylation of 1-alkenes using formaldehyde as the syngas substitute to give hydroformylated aldehydes with excellent regioselectivities. A high regioselectivity (linear/branched=up to 98/2) and chemical yield (up to 95%) can be achieved by the simultaneous use of two types of phosphanes as ligands.

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