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Communication
Synthesis and Application of Polymer-Supported Chiral Brønsted Acid Organocatalysts
Article first published online: 9 FEB 2010
DOI: 10.1002/adsc.200900746
Copyright © 2010 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
Additional Information
How to Cite
Rueping, M., Sugiono, E., Steck, A. and Theissmann, T. (2010), Synthesis and Application of Polymer-Supported Chiral Brønsted Acid Organocatalysts. Adv. Synth. Catal., 352: 281–287. doi: 10.1002/adsc.200900746
Publication History
- Issue published online: 17 FEB 2010
- Article first published online: 9 FEB 2010
- Manuscript Revised: 12 DEC 2009
- Manuscript Received: 29 OCT 2009
Funded by
- European Research Council. Grant Number: ERC 209437
- DFG
- RWTH Aachen University
- Evonik-Degussa
Keywords:
- BINOL phosphate;
- heterogeneous catalysis;
- immobilization;
- organocatalysis;
- polymers
Abstract
A new methodology for the immobilization of chiral Brønsted acids has been developed. The resulting heterogeneous organocatalysts have been employed in multiple consecutive catalysis cycles in the asymmetric organocatalytic transfer hydrogenation. The new catalyst system can not only be easily recovered from the reaction mixture in a tea-bag approach but it can also be easily reused in several catalytic cycles without loss of reactivity and selectivity.