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Keywords:

  • aldehydes;
  • homogeneous catalysis;
  • one-pot synthesis;
  • palladium(II) acetate;
  • primary amides

Abstract

The palladium-catalyzed one-pot conversion of aldehydes into primary amides in the presence of hydroxylamine hydrochloride in aqueous dimethyl sulfoxide (DMSO) at moderate temperature is described. The process is selective and free from the addition of an external chelating ligand.