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Direct C-3-Alkenylation of Quinolones via Palladium-Catalyzed C[BOND]H Functionalization

Authors

  • Mingzong Li,

    1. Department of Chemistry and Chemical Biology, Indiana University–Purdue University Indianapolis, Indianapolis, Indiana 46202-3274, USA, Fax: (+1)-317-274-4701
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  • Liangxi Li,

    1. Department of Chemistry and Chemical Biology, Indiana University–Purdue University Indianapolis, Indianapolis, Indiana 46202-3274, USA, Fax: (+1)-317-274-4701
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  • Haibo Ge

    1. Department of Chemistry and Chemical Biology, Indiana University–Purdue University Indianapolis, Indianapolis, Indiana 46202-3274, USA, Fax: (+1)-317-274-4701
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Abstract

An unprecedented C-3-alkenylation of quinolones was reported through palladium-catalyzed C[BOND]H functionalization with 1% catalyst loading. This method provides an efficient route to a variety of new quinolone derivatives.

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