Catalytic Decarboxylative Cross-Ketonisation of Aryl- and Alkylcarboxylic Acids using Magnetite Nanoparticles

Authors

  • Lukas J. Gooßen,

    Corresponding author
    1. FB Chemie – Organische Chemie, TU Kaiserslautern, Erwin-Schrödinger-Str. Geb. 54, 67663 Kaiserslautern, Germany, Fax: (+49)-631-205-3921
    • FB Chemie – Organische Chemie, TU Kaiserslautern, Erwin-Schrödinger-Str. Geb. 54, 67663 Kaiserslautern, Germany, Fax: (+49)-631-205-3921
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  • Patrizia Mamone,

    1. FB Chemie – Organische Chemie, TU Kaiserslautern, Erwin-Schrödinger-Str. Geb. 54, 67663 Kaiserslautern, Germany, Fax: (+49)-631-205-3921
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  • Christoph Oppel

    1. FB Chemie – Organische Chemie, TU Kaiserslautern, Erwin-Schrödinger-Str. Geb. 54, 67663 Kaiserslautern, Germany, Fax: (+49)-631-205-3921
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Abstract

In the presence of catalytic amounts of magnetite nanopowder, mixtures of aromatic and aliphatic carboxylic acids are converted selectively into the corresponding aryl alkyl ketones. As by-products, only carbon dioxide and water are released. This catalytic cross-ketonisation allows the regioselective acylation of aromatic systems and, thus, represents a sustainable alternative to Friedel–Crafts acylations.

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