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Keywords:

  • C[BOND]C coupling;
  • enynes;
  • green chemistry;
  • palladium;
  • stannanes

Abstract

The palladium-catalyzed reaction of alkynyltin compounds with allylic chlorides leads to a 2:2 coupling to give trienynes by regio- and stereoselective formation of three new C[BOND]C bonds. The reaction can be applied to different alkynyl and allylic fragments, providing a wide range of trienynes with different substitution patterns in very good yields. They can be prepared in a green way using recyclable polymeric tin alkynyls.