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Selective Formation of Formamidines or 7-Aminomethylbenzoxazoles from Unprecedented Couplings between Benzoxazoles and Amines

Authors

  • Dingyi Yu,

    1. Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore, Fax: (65)-6478-9080; phone: (+65)-6824-7162
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  • Szehui Lee,

    1. Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore, Fax: (65)-6478-9080; phone: (+65)-6824-7162
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  • Yin Ngai Sum,

    1. Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore, Fax: (65)-6478-9080; phone: (+65)-6824-7162
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  • Yugen Zhang

    Corresponding author
    1. Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore, Fax: (65)-6478-9080; phone: (+65)-6824-7162
    • Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore 138669, Singapore, Fax: (65)-6478-9080; phone: (+65)-6824-7162
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Errata

This article is corrected by:

  1. Errata: Corrigendum: Selective Formation of Formamidines or 7-Aminomethylbenzoxazoles from Unprecedented Couplings between Benzoxazoles and Amines Volume 354, Issue 10, 1845, Article first published online: 9 July 2012

Abstract

A method for the selective synthesis of amidines by ring-opening amination or of 7-aminomethylbenzoxazoles via a novel three-component-coupling reaction (arene, dichloromethane and amine) from benzoxazoles and amines was developed. Amidines could be further converted into 2-aminobenzoxazoles in high yield.

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