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Keywords:

  • acetylenedicarboxylate derivatives;
  • asymmetric conjugate addition;
  • 3,3a-dihydro-2H-pyrrolo[3,4-c]quinoline-1,4(5H,9bH)-diones;
  • oxindoles;
  • tertiary amine-urea catalyst

Abstract

A Z/E-selective and enantioselective conjugate addition of oxindoles to butyl but-2-ynedioate derivatives has been developed, providing a facile access to enantioenriched multifunctional olefins, which can be further converted into 3,3a- dihydro-2H-pyrrolo[3,4-c]quinoline-1,4(5H,9bH)-dione derivatives via conventional operations.