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Carboxylate-Directed C[BOND]H Functionalization

Authors

  • Guangfa Shi,

    1. The Department of Chemistry, Tongji University, 1239 Siping Road, Shanghai 200092, People's Republic of China, Fax: (+86)-21-6598-9295; phone: (+86)-21-6598-9295
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  • Yanghui Zhang

    Corresponding author
    1. The Department of Chemistry, Tongji University, 1239 Siping Road, Shanghai 200092, People's Republic of China, Fax: (+86)-21-6598-9295; phone: (+86)-21-6598-9295
    2. Key Laboratory of Yangtze River Water Environment, Ministry of Education, 1239 Siping Road, Shanghai 200092, People's Republic of China
    • The Department of Chemistry, Tongji University, 1239 Siping Road, Shanghai 200092, People's Republic of China, Fax: (+86)-21-6598-9295; phone: (+86)-21-6598-9295===

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Errata

This article is corrected by:

  1. Errata: Corrigendum: Carboxylate-Directed C[BOND]H Functionalization Volume 356, Issue 8, 1659, Article first published online: 21 May 2014

Abstract

As a widely existing functional group in organic molecules, the carboxyl group has numerous advantageous characteristics such as great convenience for further transformation, relatively low toxicity and cost, and weak coordination to transition metal catalysts, which render it an attractive directing group in transition metal-catalyzed C[BOND]H bond functionalization reactions. This review surveys transition metal-catalyzed C[BOND]H bond functionalization reactions directed by carboxylates, including carbon-carbon, carbon-oxygen, and other carbon-heteroatom bond formation reactions. Reactions directed by the acidic N-arylamides, which are derived from carboxylic acids and have a directing mode similar to that of carboxylates, are also presented here.

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