Advanced Synthesis & Catalysis

Cover image for Vol. 352 Issue 16

Special Issue: Catalytic Fluorination and Perfluoroalkylation

November 2, 2010

Volume 352, Issue 16

Pages 2677–2846

Issue edited by: Antonio Togni

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Commentary
    5. Reviews
    6. Communications
    7. Full Papers
    1. Cover Picture: (Adv. Synth. Catal. 16/2010) (page 2677)

      Version of Record online: 3 NOV 2010 | DOI: 10.1002/adsc.201090029

      Thumbnail image of graphical abstract

      The cover picture, provided by David W. C. MacMillan, shows a dual-catalytic aldehyde alkylation via photoredox organocatalysis in which electrophilic radicals (derived from the photoredox cycle; above) combine with facially biased enamine intermediates (derived from the organocatalytic cycle; below). The photoredox catalyst, Ru(bpy)32+ readily accepts a photon from a visible light source to populate the *Ru(bpy)32+ metal-to-ligand charge transfer (MLCT) excited state, eventually enabling single-electron transfer (SET) with an alkyl halide to furnish the electron-deficient alkyl radical. Simultaneously, the organocatalytic cycle is initiated upon condensation of the imidazolidinone catalyst (inset) exclusively with a non-substituted aldehyde to form a stereochemically-defined enamine. The two activation pathways merge in the key alkylation step via rapid addition of the electrophilic radical to the π-rich olefin followed by a series of concerted steps which return the organocatalyst and photocatalyst to their respective cycles and render the optically enriched α-alkyl aldehyde.

  2. Contents

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Commentary
    5. Reviews
    6. Communications
    7. Full Papers
  3. Commentary

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Commentary
    5. Reviews
    6. Communications
    7. Full Papers
  4. Reviews

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Commentary
    5. Reviews
    6. Communications
    7. Full Papers
    1. Recent Advances in Catalytic Enantioselective Fluorination Reactions (pages 2708–2732)

      Sylvain Lectard, Yoshitaka Hamashima and Mikiko Sodeoka

      Version of Record online: 26 OCT 2010 | DOI: 10.1002/adsc.201000624

      Thumbnail image of graphical abstract
    2. Stereoselective Synthesis of α-Fluorinated Amino Acid Derivatives (pages 2733–2744)

      Atsushi Tarui, Kazuyuki Sato, Masaaki Omote, Itsumaro Kumadaki and Akira Ando

      Version of Record online: 26 OCT 2010 | DOI: 10.1002/adsc.201000506

      Thumbnail image of graphical abstract
  5. Communications

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Commentary
    5. Reviews
    6. Communications
    7. Full Papers
    1. Recyclable Polymer-Supported Iodobenzene-Mediated Electrocatalytic Fluorination in Ionic Liquid (pages 2757–2760)

      Takahiro Sawamura, Shunsuke Kuribayashi, Shinsuke Inagi and Toshio Fuchigami

      Version of Record online: 26 OCT 2010 | DOI: 10.1002/adsc.201000501

      Thumbnail image of graphical abstract
    2. Chiral Brønsted Acid-Catalyzed Enantioselective Friedel–Crafts Reaction of 4,7-Dihydroindoles with Trifluoromethyl Ketones (pages 2773–2777)

      Teng Wang, Guang-Wu Zhang, Yuou Teng, Jing Nie, Yan Zheng and Jun-An Ma

      Version of Record online: 26 OCT 2010 | DOI: 10.1002/adsc.201000510

      Thumbnail image of graphical abstract
    3. Multicomponent Synthesis of Peptide-Sugar Conjugates Incorporating Hexafluorovaline (pages 2791–2798)

      Maria Cristina Bellucci and Alessandro Volonterio

      Version of Record online: 30 SEP 2010 | DOI: 10.1002/adsc.201000489

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  6. Full Papers

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Commentary
    5. Reviews
    6. Communications
    7. Full Papers
    1. Divergent Preparation of Fluoroalkylated Sulfilimine and Sulfilimino Iminium Salts (pages 2805–2814)

      Céline Urban, Yohan Macé, Frédéric Cadoret, Jean-Claude Blazejewski and Emmanuel Magnier

      Version of Record online: 26 OCT 2010 | DOI: 10.1002/adsc.201000494

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    2. Synthesis of β-Trifluoromethylated Δ1-Pyrrolines (pages 2825–2830)

      Olivier Marrec, Carole Christophe, Thierry Billard, Bernard Langlois, Jean-Pierre Vors and Sergii Pazenok

      Version of Record online: 23 SEP 2010 | DOI: 10.1002/adsc.201000487

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    3. A New and Direct Trifluoromethoxylation of Aliphatic Substrates with 2,4-Dinitro(trifluoromethoxy)benzene (pages 2831–2837)

      Olivier Marrec, Thierry Billard, Jean-Pierre Vors, Sergii Pazenok and Bernard R. Langlois

      Version of Record online: 22 SEP 2010 | DOI: 10.1002/adsc.201000488

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