You have free access to this content

Advanced Synthesis & Catalysis

Copyright © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim

Cover image for Vol. 354 Issue 1

January 2012

Volume 354, Issue 1

Pages 1–222

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Commentary
    4. Contents
    5. Review
    6. Communications
    7. Full Papers
    8. Updates
    1. You have free access to this content
      Cover Picture: (Adv. Synth. Catal. 1/2012) (page 1)

      Article first published online: 20 JAN 2012 | DOI: 10.1002/adsc.201290000

      Thumbnail image of graphical abstract

      The cover picture, provided by Qi-Lin Zhou, shows the example of an exceptionally highly efficient chiral catalyst. The catalyst is a very stable dihydride iridium complex of a tridentate chiral spiro P-N-N ligand based on the 1,1′-spirobiindane skeleton, which exhibits excellent enantioselectivity and extremely high turnover number (in excess of one million) for the hydrogenation of both aryl ketones and β-aryl-β-keto esters. Although little is known about the mechanism of this iridiumcatalyzed carbonyl group hydrogenation reaction, a non-classical metal[BOND]ligand bifunctional mechanism deserves to be recommended to interpret the high efficiency of this catalyst. With the help of KO-t-Bu and under an H2 atmosphere, the dihydride iridium complex is converted to a trihydride iridium complex. After combination of the substrate with the trihydride iridium complex, a cyclic six-membered transition state is formed. The hydridic Ir[BOND]H and protic N[BOND]H of the catalyst are simultaneously transferred to the carbonyl[BOND]oxygen double bond of the substrate, resulting in a chiral alcohol and a hydrido amido iridium complex. Finally, the hydrido amido iridium complex is hydrogenated with H2 to regenerate the trihydride iridium complex.

  2. Commentary

    1. Top of page
    2. Cover Picture
    3. Commentary
    4. Contents
    5. Review
    6. Communications
    7. Full Papers
    8. Updates
    1. You have free access to this content
      New Developments in Advanced Synthesis & Catalysis: Growth and High-Impact Research for Green Organic Synthesis (pages 3–7)

      Joe P. Richmond

      Article first published online: 13 JAN 2012 | DOI: 10.1002/adsc.201101001

      Thumbnail image of graphical abstract

  3. Contents

    1. Top of page
    2. Cover Picture
    3. Commentary
    4. Contents
    5. Review
    6. Communications
    7. Full Papers
    8. Updates
    1. You have free access to this content
      Graphical Abstract: Adv. Synth. Catal. 1/2012 (pages 9–14)

      Article first published online: 20 JAN 2012 | DOI: 10.1002/adsc.201290001

  4. Review

    1. Top of page
    2. Cover Picture
    3. Commentary
    4. Contents
    5. Review
    6. Communications
    7. Full Papers
    8. Updates
    1. You have free access to this content
      Flow Chemistry – A Key Enabling Technology for (Multistep) Organic Synthesis (pages 17–57)

      Jens Wegner, Sascha Ceylan and Andreas Kirschning

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100584

      Thumbnail image of graphical abstract

  5. Communications

    1. Top of page
    2. Cover Picture
    3. Commentary
    4. Contents
    5. Review
    6. Communications
    7. Full Papers
    8. Updates
    1. You have free access to this content
      SIAPhos: Phosphorylated Sulfonimidamides and their Use in Iridium-Catalyzed Asymmetric Hydrogenations of Sterically Hindered Cyclic Enamides (pages 59–64)

      Frederic W. Patureau, Christin Worch, Maxime A. Siegler, Anthony L. Spek, Carsten Bolm and Joost N. H. Reek

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100692

      Thumbnail image of graphical abstract
    2. You have free access to this content
      Stereoselective Epoxidation of Alkenes with Hydrogen Peroxide using a Bipyrrolidine-Based Family of Manganese Complexes (pages 65–70)

      Isaac Garcia-Bosch, Laura Gómez, Alfonso Polo, Xavi Ribas and Miquel Costas

      Article first published online: 29 NOV 2011 | DOI: 10.1002/adsc.201100409

      Thumbnail image of graphical abstract
    3. You have free access to this content
      A Mild, Highly Efficient Addition of Alkynes to Aldehydes Catalyzed by Titanium Dioxide-Supported Silver Nanoparticles (pages 71–76)

      Min Yu, Yong Wang, Weijiang Sun and Xiaoquan Yao

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100518

      Thumbnail image of graphical abstract
    4. You have free access to this content
      Copper-Mediated One-Pot Transformation of 2-N-Sulfonyl- aminoaryl Diselenides into Benzo[b][1,4]selenazines (pages 77–82)

      Caterina Viglianisi, Lavinia Simone and Stefano Menichetti

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100587

      Thumbnail image of graphical abstract
    5. You have free access to this content
      Palladacycle-Catalyzed Tandem Allylic Amination/Allylation Protocol for One-Pot Synthesis of 2-Allylanilines from Allylic Alcohols (pages 83–87)

      Ke Chen, Yongxin Li, Sumod A. Pullarkat and Pak-Hing Leung

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100424

      Thumbnail image of graphical abstract

  6. Full Papers

    1. Top of page
    2. Cover Picture
    3. Commentary
    4. Contents
    5. Review
    6. Communications
    7. Full Papers
    8. Updates
    1. You have free access to this content
      Evolutionary Catalyst Screening: Iridium-Catalyzed Imine Hydrogenation (pages 89–95)

      Alexander M. Kluwer, Remko J. Detz, Zohar Abiri, Alida M. van der Burg and Joost N. H. Reek

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100422

      Thumbnail image of graphical abstract
    2. You have free access to this content
      Production, Characterization and Synthetic Application of a Purine Nucleoside Phosphorylase from Aeromonas hydrophila (pages 96–104)

      Daniela Ubiali, Carla D. Serra, Immacolata Serra, Carlo F. Morelli, Marco Terreni, Alessandra M. Albertini, Paolo Manitto and Giovanna Speranza

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100505

      Thumbnail image of graphical abstract
    3. You have free access to this content
      Stereochemical Outcome of the Biocatalysed Reduction of Activated Tetrasubstituted Olefins by Old Yellow Enzymes 1–3 (pages 105–112)

      Elisabetta Brenna, Francesco G. Gatti, Daniela Monti, Fabio Parmeggiani and Stefano Serra

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100504

      Thumbnail image of graphical abstract
    4. You have free access to this content
      Application of a Recombinant Escherichia coli Whole-Cell Catalyst Expressing Hydroxynitrile Lyase and Nitrilase Activities in Ionic Liquids for the Production of (S)-Mandelic Acid and (S)-Mandeloamide (pages 113–122)

      Stefanie Baum, Fred van Rantwijk and Andreas Stolz

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100391

      Thumbnail image of graphical abstract
    5. You have free access to this content
      Glucose 1-Phosphate Thymidylyltransferase in the Synthesis of Uridine 5′-Diphosphate Galactose and its Application in the Synthesis of N-Acetyllactosamine (pages 123–132)

      Wei-Ting Chien, Chien-Fu Liang, Ching-Ching Yu, Jian- Hong Lin, Haung-Ting Wu and Chun-Cheng Lin

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100402

      Thumbnail image of graphical abstract
    6. You have free access to this content
      On Homogeneous Gold/Palladium Catalytic Systems (pages 133–147)

      A. Stephen K. Hashmi, Christian Lothschütz, René Döpp, Martin Ackermann, Janosc De Buck Becker, Matthias Rudolph, Christian Scholz and Frank Rominger

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201000044

      Thumbnail image of graphical abstract
    7. You have free access to this content
      Dimerization of Terminal Arylalkynes in Aqueous Medium by Ruthenium and Acid Promoted (RAP) Catalysis: Acetate- Assisted (sp)C[BOND](sp2)C Bond Formation (pages 148–158)

      Alessandra Coniglio, Mauro Bassetti, Sergio E. García-Garrido and José Gimeno

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100600

      Thumbnail image of graphical abstract
    8. You have free access to this content
      Palladium(II)/Copper Halide/Solvent Combination for Selective Intramolecular Domino Reactions of Indolecarboxylic Acid Allylamides: An Unprecedented Arylation/Esterification Sequence (pages 159–170)

      Gianluigi Broggini, Vincenzina Barbera, Egle M. Beccalli, Elena Borsini, Simona Galli, Giuseppe Lanza and Gaetano Zecchi

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100614

      Thumbnail image of graphical abstract
    9. You have free access to this content
      Generation of 11-Fluoro-11H-indeno[1,2-c]quinolines via a Palladium-Catalyzed Three-Component Reaction of 2-Alkynylbromobenzenes, 2-Alkynylanilines, and N-Fluorobenzenesulfonimide (pages 171–178)

      Xiaolin Pan, Yong Luo, Gang Liu, Shouzhi Pu and Jie Wu

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100582

      Thumbnail image of graphical abstract
    10. You have free access to this content
      Tandem Platinum Dichloride Catalysis and Thermal Reaction of Enynes: Versatile Synthetic Platform Based on Bicyclo[4.1.0]hept-2-enes (pages 179–186)

      Sun Young Kim, Yujung Park, Sori Son and Young Keun Chung

      Article first published online: 13 JAN 2012 | DOI: 10.1002/adsc.201100694

      Thumbnail image of graphical abstract
    11. You have free access to this content
      Microwave-Enhanced Efficient Regioselective Synthesis of 1,3,4-Trisubstituted 2-Mercaptoimidazoles on a Soluble Support (pages 187–196)

      Gorakh S. Yellol, Cheng-Ting Chou, Wang-Jin Chang, Barnali Maiti and Chung-Ming Sun

      Article first published online: 13 JAN 2012 | DOI: 10.1002/adsc.201100640

      Thumbnail image of graphical abstract
    12. You have free access to this content
      Direct Asymmetric Aldol Reactions in Water Catalysed by a Highly Active C2-Symmetrical Bisprolinamide Organocatalyst (pages 197–204)

      Joshua P. Delaney and Luke C. Henderson

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100667

      Thumbnail image of graphical abstract

  7. Updates

    1. Top of page
    2. Cover Picture
    3. Commentary
    4. Contents
    5. Review
    6. Communications
    7. Full Papers
    8. Updates
    1. You have free access to this content
      Domino Carbopalladation-Carbonylation: Investigation of Substrate Scope (pages 205–216)

      Brinton Seashore-Ludlow, Jakob Danielsson and Peter Somfai

      Article first published online: 13 JAN 2012 | DOI: 10.1002/adsc.201100678

      Thumbnail image of graphical abstract
    2. You have free access to this content
      Efficient and Selective Hydrosilylation of Carbonyl Compounds Catalyzed by Iron Acetate and N-Hydroxyethylimidazolium Salts (pages 217–222)

      Elina Buitrago, Fredrik Tinnis and Hans Adolfsson

      Article first published online: 12 JAN 2012 | DOI: 10.1002/adsc.201100606

      Thumbnail image of graphical abstract

SEARCH

SEARCH BY CITATION