Advanced Synthesis & Catalysis

Cover image for Vol. 354 Issue 17

November 26, 2012

Volume 354, Issue 17

Pages 3133–3332

  1. Cover Picture

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Reviews
    5. Communications
    6. Full Papers
    7. Update
    1. You have free access to this content
      Cover Picture: (Adv. Synth. Catal. 17/2012) (page 3133)

      Article first published online: 19 NOV 2012 | DOI: 10.1002/adsc.201290033

      Thumbnail image of graphical abstract

      The cover picture, provided by Peter Allen and Bruce Lipshutz (UCSB), illustrates an asymmetric conjugate addition of an arylboronic acid to an enone. The key contribution focuses on a nonracemic (R-BINAP)-ligated rhodium catalyst that is covalently tethered to the ubiquinol-derived platform PQS, thereby forming “PQS-BINAP-Rh”. This new species spontaneously dissolves in water to form micelles that function as nanoreactors in which the 1,4-additions take place. These reactions occur at room temperature within the lipophilic cores of these nanoparticles to afford the expected high levels of ees. When complete, the product is extracted from the water directly from the reaction vessel with small amounts of a single organic solvent. Virtually none (i.e., ppb) of the rhodium is lost to the product upon extraction. The water can be recycled without its removal from the reaction vessel. This enabling technology, therefore, allows for valued asymmetric homogeneous catalysis to be run in the absence of organic solvents, with no investment in energy in the form of heating or cooling, with in-flask recycling of both the aqueous medium and a costly catalyst, and with no contamination of the desired product by a transition metal. This methodology is illustrated in the communication by Lipshutz and co-workers on pages 3175–3179.

  2. Contents

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Reviews
    5. Communications
    6. Full Papers
    7. Update
    1. Graphical Abstract: Adv. Synth. Catal. 17/2012 (pages 3135–3139)

      Article first published online: 19 NOV 2012 | DOI: 10.1002/adsc.201290034

  3. Reviews

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Reviews
    5. Communications
    6. Full Papers
    7. Update
  4. Communications

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Reviews
    5. Communications
    6. Full Papers
    7. Update
    1. Rhodium-Catalyzed Asymmetric 1,4-Additions, in Water at Room Temperature, with In-Flask Catalyst Recycling (pages 3175–3179)

      Bruce H. Lipshutz, Nicholas A. Isley, Ralph Moser, Subir Ghorai, Helena Leuser and Benjamin R. Taft

      Article first published online: 29 JUL 2012 | DOI: 10.1002/adsc.201200160

      Thumbnail image of graphical abstract
    2. Formic Acid: A Promising Bio-Renewable Feedstock for Fine Chemicals (pages 3180–3186)

      Manuel G. Mura, Lidia De Luca, Giampaolo Giacomelli and Andrea Porcheddu

      Article first published online: 8 NOV 2012 | DOI: 10.1002/adsc.201200748

      Thumbnail image of graphical abstract
  5. Full Papers

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Reviews
    5. Communications
    6. Full Papers
    7. Update
    1. Palladium-Catalyzed Highly Regioselective Arylation of Allylamines with Thiophenes and Furans (pages 3225–3230)

      Zhen Jiang, Lingjuan Zhang, Chaonan Dong, Zhongzheng Cai, Weijun Tang, Huanrong Li, Lijin Xu and Jianliang Xiao

      Article first published online: 13 NOV 2012 | DOI: 10.1002/adsc.201200470

      Thumbnail image of graphical abstract
    2. An Ion-Pair Immobilization Strategy in Rhodium-Catalyzed Asymmetric Transfer Hydrogenation of Aromatic Ketones (pages 3250–3258)

      Yulong Xu, Tanyu Cheng, Jie Long, Ketang Liu, Qingqian Qian, Fei Gao, Guohua Liu and Hexing Li

      Article first published online: 12 NOV 2012 | DOI: 10.1002/adsc.201200320

      Thumbnail image of graphical abstract
    3. Efficient Room-Temperature Oxidation of Hydrocarbons Mediated by Tricopper Cluster Complexes with Different Ligands (pages 3275–3282)

      Penumaka Nagababu, Suman Maji, Manyam Praveen Kumar, Peter P.-Y. Chen, Steve S.-F. Yu and Sunney I. Chan

      Article first published online: 13 NOV 2012 | DOI: 10.1002/adsc.201200474

      Thumbnail image of graphical abstract
    4. Non-Enzymatic Geometry-Selective Acylation of Tri- and Tetrasubstituted α,α′-Alkenediols (pages 3291–3298)

      Keisuke Yoshida, Kenji Mishiro, Yoshihiro Ueda, Takashi Shigeta, Takumi Furuta and Takeo Kawabata

      Article first published online: 13 NOV 2012 | DOI: 10.1002/adsc.201200242

      Thumbnail image of graphical abstract
  6. Update

    1. Top of page
    2. Cover Picture
    3. Contents
    4. Reviews
    5. Communications
    6. Full Papers
    7. Update

SEARCH

SEARCH BY CITATION