Design of formulated products: A systematic methodology

Authors

  • Elisa Conte,

    1. CAPEC, Dept. of Chemical and Biochemical Engineering, Technical University of Denmark, DK-2100 Lyngby, Denmark
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  • Rafiqul Gani,

    Corresponding author
    1. CAPEC, Dept. of Chemical and Biochemical Engineering, Technical University of Denmark, DK-2100 Lyngby, Denmark
    • CAPEC, Dept. of Chemical and Biochemical Engineering, Technical University of Denmark, DK-2100 Lyngby, Denmark
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  • Ka Ming Ng

    1. Dept. of Chemical and Biomolecular Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong
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Abstract

In chemical product design one tries to find a product which exhibits the desired (target) behavior specified a priori. The identity of the ingredients of chemical-based products maybe unknown at the start, but some of their desired qualities and functions are usually known. A systematic model-based computer-aided methodology for design and verification of a class of chemical-based products (liquid formulations) is presented. This methodology is part of an integrated three-stage approach for design/verification of liquid formulations where stage-1 generates a list of feasible product candidates and/or verifies a specified set through a sequence of predefined activities (work-flow). Stage-2 and stage-3 (not presented here) deal with the planning and execution of experiments, for product validation. Four case studies have been developed to test the methodology. The computer-aided design (stage-1) of a paint formulation and an insect repellent lotion are presented. © 2011 American Institute of Chemical Engineers AIChE J, 2011

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