Particle Technology and Fluidization

Powder hydrophobicity and flow properties: Effect of feed frame design and operating parameters

  1. Rafael Mendez1,*,
  2. Fernando J. Muzzio2,
  3. Carlos Velazquez1

Article first published online: 27 APR 2011

DOI: 10.1002/aic.12639

Issue

AIChE Journal

AIChE Journal

Volume 58, Issue 3, pages 697–706, March 2012

Additional Information

How to Cite

Mendez, R., Muzzio, F. J. and Velazquez, C. (2012), Powder hydrophobicity and flow properties: Effect of feed frame design and operating parameters. AIChE J., 58: 697–706. doi: 10.1002/aic.12639

Author Information

  1. 1

    Dept. of Chemical Engineering, University of Puerto Rico, Mayaguez, Call Box 9000 Mayaguez, PR 00681

  2. 2

    Dept. of Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854

*Dept. of Chemical Engineering, University of Puerto Rico, Mayaguez, Call Box 9000 Mayaguez, PR 00681

Publication History

  1. Issue published online: 6 FEB 2012
  2. Article first published online: 27 APR 2011
  3. Accepted manuscript online: 30 MAR 2011 08:58AM EST
  4. Manuscript Revised: 23 MAR 2011
  5. Manuscript Received: 28 SEP 2010

Funded by

  • NSF ERC. Grant Number: EEC-0540855

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Keywords:

  • powder feeders;
  • die filling;
  • shear rate;
  • overlubrication;
  • tablet hardness;
  • dissolution

Abstract

The effect of feed frames, a device used in rotary tablet presses to drive the powders into compression dies, on the properties of the powders entering the dies is systematically described in this article. The work focuses on the effect of blend composition, feed frame parameters (blade speed and residence time), and rotary die disc parameters (die disc speed and die diameter) on powder overlubrication, the flow properties of the blends, and the resulting tablet properties (tablet hardness and dissolution). For lubricated blends, the feed frame had a large impact on powder hydrophobicity and powder flow properties. Hydrophobicity results demonstrated that the shear applied by the feed frame caused overlubrication of the powders, which improved the powder flow properties but affected adversely the tablet hardness and dissolution. © 2011 American Institute of Chemical Engineers AIChE J, 2012

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